Equine herpesvirus 4 (EHV-4) is a common DNA virus in horse populations globally. It is most commonly associated with respiratory infection in young horses in higher density populations and is a biosecurity concern due to outbreaks. Symptoms include fever, anorexia, inflammation of lymph nodes and extensive nasal discharge. It is notable that severe economic strain can be seen in the equine industry from EHV-4 due to lost training time, secondary pneumonia and sporadic abortion. 1 Further, latent infection and stress-induced shedding is characteristic of the herpes virus subtypes. 1,2Current diagnostic testing requires use of PCR for specific diagnosis as clinical signs of EHV-4 mimic that of equine influenza, EHV-1 and other respiratory pathogens. EHV-1 imposes further risk due to potentially neuropathic disease thus providing the necessity for species discrimination during diagnosis. 2The Fluxergy EHV-4 assay provides reliable detection of the herpes subtype in deep nasopharyngeal swabs identifying EHV-4 in horses with respiratory symptoms and horses that have been previously exposed to the virus. 3
- Rush, B. R. (2016). Equine Herpesvirus Infection. Retrieved from Merck Veterinary Manual.
- Pusterla, N., Leutenegger, C. M., Wilson, W. D., Watson, J. L., Ferraro, G. L., & Madigan, J. E. (2005). Equine herpesvirus-4 kinetics in peripheral blood leukocytes and nasopharyngeal secretions in foals using quantiative real-time TaqMan PCR. J Vet Diagn Invest, 17, 578-81.
- Patel, J. R., & Haldens, J. (2005). Equine herpesviruses 1 (EHV-1) and 4 (EHV-4)--epidemiology, disease and immunoprophylaxis: a brief review. Veterinary Journal, 1, 14-23.