Lawsonia intracellularis is an intracellular, gram-negative, bacteria that causes Equine Proliferative Enteropathy (EPE) worldwide, and can effect foals, pigs, rodents, and ratites. This disease in foals is also called “Lawsonia” and can survive in the environment for 2 weeks. Transmission may occur by fecal to oral route. Infective signs include: proliferative enteropa-thy, diarrhea, rapid weight loss, colic, lethargy, and subcutaneous edema in weaning foals. Foals 4-6 months are commonly infected, but L. intracellularis may infect foals under a year old. Infected foals may obtain a secondary infection in the gastro intestinal tract, skin, or respiratory tract. Diagnosis of L. intracellularis can be confirmed using Polymerase Chain Reaction (PCR), immunohistochemistry, serology, and ELISA. However, it is recommended that PCR and serology be ordered. Treatment of L. intracellularis with oxytetracycline, followed by doxycycline has been previously effective. This Fluxergy L. intracellularis PCR assay has been designed to target a conserved region of this bacteria and allow for rapid detection of the pathogen within close proximity of the patient.