C. difficile is a gram positive spore-forming bacteria and is the leading cause of hospital-acquired enteritis. In particular, pathogenic C. difficile is a causative agent of several antibiotic-associated diarrheal diseases commonly induced by treatment with antibiotics or by disruption of endogenous gastrointestinal flora. In the US alone, greater than 250,000 disease cases can be seen every year with associated annual healthcare costs exceeding US $1 billion.1 The worldwide burden is further troublesome. The main method of virulence and pathogenicity is due to expression of exotoxins, specifically by genes TcdA and TcdB. Both toxins, A and B specifically, are proinflammatory and cytotoxic resulting in fluid accumulation and extensive damage to the large intestine. 2 Improved detection of pathogenic C. difficile is recommended via PCR due to sensitivity and specificity. Fluxergy’s rapid diagnostic test is pathogen toxin specific and provides reliable detection in a point-of-use format.